You can use these instructions to use a rectal suppository yourself. If youre a parent or caregiver, you can also use these steps to give a suppository to a child or another adult. Suppositories arent scary, theyre just a different way to deliver medicine. To put in a rectal suppository go to the bathroom first to try to empty your colon. When oral medications are ineffective, rectal suppositories are often needed to relieve severe constipation. A suppository is a medication that is inserted into the rectum, vagina, or urethra to be broken down and absorbed by the body. 2 if the suppository is soft, hold it under cool water or place it in a refrigerator for a few minutes to harden it before removing the wrapper. 4 if you were told to use half of the suppository, cut it lengthwise with a clean, single-edge razor blade. to insert suppository first remove the foil wrapper and moisten the suppository with cold water. Lie down on your side and use your finger to push the suppository well up into the rectum. Results often may be obtained with bisacodyl suppositories in 15 minutes to 1 hour. lie down and rest for up to 15 minutes to give the suppository time to be absorbed. Step 8 wait to use the restroom wait to use the restroom for at least one hour after insertion. Foria explore is a latex-friendly suppository that has almighty rectum-relaxing and nerve-calming. Use this medicine (glycerin suppositories) as ordered by your doctor. If suppository is soft, chill in a refrigerator or run cold water over it.